Windows Vista Computer Very Slow and Hanging Up

Hi,
I brought home my friend's Vista Computer to try to get it running better as she can not afford to buy a new one right now.
She has told me that it takes at least 10 times for her to get the computer to start up, also it hangs up on various programs and it is very very slow.
I brought it home last night and have been trying to do a little cleaning with Windows security Essentials and Malware Bytes (no problems). When I ran Malware Bytes the first time it said I deleted 14 of 16 potential problems. I then ran it in Safe Mode and it only found one so now I am running it again.

I did take pictures of the Threats, such as:
PUP.Optional.Updater c:\users\Patricia\AppData\Roaming\UpdaterEX\Update Proc

I did supposedly delete this problem.

Then I looked at threads that were quarteened and deleted the following:
PUP.Optional.Amonetize-Registry Key
PUP.Optional.Amonetize-Registry Key
PUP.Optional.Amonetize-Registry Key
PUP.Optional.Updater-Folder
PUP.Optional DealPly-File

I just finished running the Malware-Bytes again in Safe Mode and it said no threats were detected but I am sure something is hiding in the background.

Please advise me what I should do to help my friend.

Thanks, Jean

 

Heed PeteC's advice. If it's in the registry you can be sure there may be are a lot more infected hidden registry keys lurking in there than what was found by your search.