Windows Vista Programs cannot connect to the internet

Hello, i have Vista home premium 32bit.
Now sadly i have a few game clients and anti virus software on my computer that have been recently unable to connect cot there servers whether they are updating or just trying to connect, ive checked the firewall not the problem, but around the same time this was happening i Spywaredoctor got infected and i had to delete it, that all i know sofar but other programs like Firefox and limewire are unaffected and can connect perfectly can somebody help??