Here is a useful resource on VM. http://aumha.org/win5/a/xpvm.php As rsinfo said, the swap file or virtual memory is a part of your Hard Disk...
Once u clean out the nasties, you might also want to try booting with just ur AV and firewall. How much RAm is this system running on? Also after...
Go to start>Run >Msconfig hit enter Here is a startup list guide that you can use, or just google the entries u need to check...
Run a disk cleanup and defragment the HDD,, if its loaded with junk and cluttered, things can slowdown. Infact do it regularly....
Separate names with a comma.