E drive not being detected on computer

I have searched the forum with little success. My E drive on my computer is not picking up when I start up. What is so strange is that sometimes it may show up, when I click on "my computer ", and sometimes it will not. I have not had this computer long, and have taken it back to store numerous times, but when they look at it, the E drive is there!!! They say that it probably something that I have hooked up to it that is causing a conflict. This has gotten old, because I live quite a distance from the store and I really have to get this matter solved. I have a Deskjet 932C printer, and a Canon Color Image Scanner N670U hooked up, and a cordless mouse. I tried unplugging everything except the mouse, to see if that was my problem. Well, it did not work, and still no E Drive. I have windows XP system. I am at the point where if I have to buy a new printer, or scanner I will, but I just want to make sure that is the problem before I start spending money again. Even with the warranty still on my computer I am thinking about taking it to another repair shop and see just what they have to say about the matter. Any help will be greatley appreciated.

 

I'm sorry. It is my DVD drive.

 

Try resetting the filters:
http://support.microsoft.com/kb/314060

 

E-Drive Recognition

1. unplug power cable
2.Unplug USB cable at PC
3.Connect power cable dircetly to wall outlet
4.Connect USB cable too computer
5.Right click on my computer then click on "manage "
6., last-click on Disk management

 

In re reading his original post I note that he did not say whether the drive was either internal or external. My solution obviously applies to external drive.